Organic Letters
2007-08-30
First total synthesis and structural reassignment of (-)-aplysiallene.
Jian Wang, Brian L Pagenkopf
Index: Org. Lett. 9 , 3703, (2007)
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Abstract
The first total synthesis of (-)-aplysiallene has been completed in 16 steps and features a key sequential Mukaiyama aerobic oxidative cyclization to prepare the fused bis-THF core. The original stereochemical assignment has been revised as shown.
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