Clean and efficient microwave-solvent-free synthesis of 1-(2′, 4′-dichlorophenacyl) azoles
…, A Loupy, M Liagre, AM de Guzzi Plepis, PJ Cordeiro
Index: Perez, Eduardo R.; Loupy, Andre; Liagre, Marion; De Guzzi Plepis, Ana M.; Cordeiro, Paulo J. Tetrahedron, 2003 , vol. 59, # 6 p. 865 - 870
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Citation Number: 23
Abstract
Microwave induced N-alkylation of several azoles with 2, 2′, 4′-trichloroacetophenone (TCA) under solvent-free conditions allowed to obtain the corresponding 1-(2′, 4′- dichlorophenacyl) azoles with satisfactory to good selectivities and yields. TGA and DSC measurements were achieved for the synthesized compounds and showed a close relationship between the thermal behavior and the reaction temperature under microwave ...
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