Tetrahydroquinoline derivatives as opioid receptor antagonists

C Zhang, SM Westaway, JD Speake, MJ Bishop…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 2 p. 670 - 676

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Abstract

... Bioorganic & Medicinal Chemistry Letters. ... a Department of Medicinal Chemistry, GlaxoSmithKline, Research ... the substitution pattern for the secondary amine side chain, compound 2o was synthesized and tested (Table 2). It is worth noting that the general chemistry used for the ...

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Tetrahydroquinoline derivatives as opioid receptor antagonists

[Zhang, Cunyu; Westaway, Susan M.; Speake, Jason D.; Bishop, Michael J.; Goetz, Aaron S.; Carballo, Luz Helena; Hu, Mike; Epperly, Andrea H. Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 2 p. 670 - 676]

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