Journal of medicinal chemistry

Imidothiazoles

LM Rice, KR Scott, CH Grogan

Index: Rice,L.M. et al. Journal of Medicinal Chemistry, 1968 , vol. 11, # 1 p. 183 - 185

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Citation Number: 1

Abstract

As part of a continuing study of various imideszp4 and their reduction products as pharmacologically active compounds, we have prepared a limited series of imides derived from% aminothiazole and related thiazoles. These imides were obtained from a wide variety of compounds of diverse structure. An example employing 1, 2-cyclohexanedicarboxylic anhydride illustrates the general method used (Scheme I). This reaction was either ...