Syntheses of model oligosaccharides of biological significance. 7. Synthesis of a fucosylated N, N'-diacetylchitobioside linked to bovine serum albumin and …

…, JF Harris, JP Carver, JJ Krepinsky

Index: Lee, Ho-Huat; Schwartz, David A.; Harris, John F.; Carver, Jeremy P.; Krepinsky, Jiri J. Canadian Journal of Chemistry, 1986 , vol. 64, p. 1912 - 1918

Full Text: HTML

Citation Number: 50

Abstract

Synthesis of methoxycarbonyloctyl 2-acetamido-4-O-[(2'-acetamido-2'-deoxy-β-d- glucopyranosyl)-6-O-α-l-fucopyranosyl]-2-deoxy-(β-d-glucopyranoside as shown in Scheme 1 is described together with coupling it with bovine serum albumin and poly-l-lysine. Mouse and rabbit antisera to the BSA conjugate were prepared and partially characterized.