Synthesis, stereochemical assignments, and biological activities of homoisoflavonoids

…, CV Rao, S Venkateswarlu, AV Krishnaraju…

Index: Siddaiah, Vidavalur; Rao, Chunduri Venkata; Venkateswarlu, Somepalli; Krishnaraju, Alluri V.; Subbaraju, Gottumukkala V. Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 8 p. 2545 - 2551

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Citation Number: 55

Abstract

A series of four naturally occurring homoisoflavonoids and eight analogs have been synthesized starting from an appropriately substituted phenol through chroman-4-one, in four steps. The products were assigned as E-isomers based on NMR spectroscopic data. The E-isomers were converted into Z-isomers by photoisomerization. The E-and Z-isomers showed distinct chemical shifts and the differences between (E) and (Z)- ...