Organic Letters 2012-11-16

α-Aryl-substituted allenamides in an imino-Nazarov cyclization cascade catalyzed by Au(I).

Zhi-Xiong Ma, Shuzhong He, Wangze Song, Richard P Hsung

Index: Org. Lett. 14(22) , 5736-9, (2012)

Full Text: HTML

Abstract

An imino-Nazarov cyclization using α-aryl-substituted allenamides is described. This gold(I)-catalyzed cascade is efficient and regioselective in constructing a diverse array of synthetically useful aromatic-ring fused cyclopentenamides. The success in this transformation represents a solution to the challenge in establishing an imino-Nazarov cyclization process.

Related Compounds

Related Articles:

Designed self-assembling peptides as templates for the synthesis of metal nanoparticles.

2013-01-01

[Methods Mol. Biol. 996 , 195-202, (2013)]

Metal patch test results from 1990-2009.

2011-03-01

[J. Dermatol. 38(3) , 267-71, (2011)]

Gold(III) chloride catalyzed regioselective synthesis of pyrano[3,4-b]indol-1(9H)-ones and evaluation of anticancer potential towards human cervix adenocarcinoma.

2011-07-15

[Bioorg. Med. Chem. Lett. 21 , 4170, (2011)]

Synthesis of bicyclic imidazoles via [2 + 3] cycloaddition between nitriles and regioselectively generated α-imino gold carbene intermediates.

2012-09-07

[Org. Lett. 14(17) , 4662-5, (2012)]

Gold(III) chloride catalysed synthesis of 5-alkylidene-dihydrothiazoles.

2011-07-07

[Org. Biomol. Chem. 9(13) , 4791-4, (2011)]

More Articles...