Acetoxylation of 6, 7-dialkoxy-substituted 1, 4-dihydroquinoxaline-2, 3-diones (Qxs) using fuming nitric acid in acetic acid: A facile synthesis of 5-acyloxy-6, 7-dialkoxy …
ZL Zhou, E Weber, JFW Keana
Index: Zhou, Zhang-Lin; Weber, Eckard; Keana, John F. W. Tetrahedron Letters, 1995 , vol. 36, # 42 p. 7583 - 7586
Full Text: HTML
Citation Number: 9
Abstract
Treatment of 6, 7-dialkoxy-1.4-dihydroquinoxaline-2.3-diones 3 with fuming nitric acid in acetic acid at 25° C resulted in an acetoxylation reaction, giving 5-acetoxy-6, 7-dialkoxy-1, 4- dihydroquinoxaline-2. 3-diones 4 in moderate yields A mechanism involving ipso attack of nitronium ion as the first step is proposed.
Related Articles:
[Park, Cheon Min; Kwon, Min Serk; Park, Jaiwook Synthesis, 2006 , # 22 p. 3790 - 3794]
6, 7-Dialkoxychinoxalin-Derivate
[Budesinsky,Z.; Valenta,A. Collection of Czechoslovak Chemical Communications, 1971 , vol. 36, p. 2527 - 2539]
[Akhtar, Yasmin; Isman, Murray B.; Paduraru, Peggy M.; Nagabandi, Srinivas; Nair, Ranjeet; Plettner, Erika Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 25 p. 10323 - 10330]