Synthesis and antitubercular activity of phenothiazines with reduced binding to dopamine and serotonin receptors

PB Madrid, WE Polgar, L Toll, MJ Tanga

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 11 p. 3014 - 3017

Full Text: HTML

Citation Number: 55

Abstract

... Please enable JavaScript to use all the features on this page. Bioorganic & Medicinal Chemistry Letters. ... Overall, these data indicate that an increase in the steric volume on the side chain reduces binding to these subtypes of the dopamine and serotonin receptors. ...

Related Articles:

Synthesis of phenothiazines from cyclohexanones and 2-aminobenzenethiols under transition-metal-free conditions

[RSC Advances, , vol. 3, # 40 p. 18605 - 18608]

Ion radicals. XXV. Reactions of thianthrene and phenothiazine perchlorates with nitrite ion, pyridine, and other nucleophiles

[Journal of Organic Chemistry, , vol. 37, p. 2691 - 2697]

More Articles...