Tetrahedron

A highly efficient palladium-catalyzed desulfitative arylation of azoles with sodium arylsulfinates

M Wang, D Li, W Zhou, L Wang

Index: Wang, Min; Li, Dengke; Zhou, Wei; Wang, Lei Tetrahedron, 2012 , vol. 68, # 7 p. 1926 - 1930

Full Text: HTML

Citation Number: 69

Abstract

A highly efficient palladium-catalyzed direct desulfitative arylation of azoles at C2-position has been developed using sodium arylsulfinates as aryl sources. Azoles including benzoxazoles, benzothiazoles, oxazoles, thiazoles, and 1, 3, 4-oxadiazoles reacted with sodium arylsulfinates smoothly to generate the corresponding products in good to excellent yields, and various substitution patterns were tolerated toward the reaction.

Related Articles:

A green route for the synthesis of 2-substituted benzoxazole derivatives catalyzed by Al 3+-exchanged K10 clay

[Suresh, Dhanusu; Dhakshinamoorthy, Amarajothi; Pitchumani, Kasi Tetrahedron Letters, 2013 , vol. 54, # 48 p. 6415 - 6419]

Poly (ethylene glycol)-bound sulphonic acid as a novel catalyst for synthesis of benzoxazoles

[Chikhale, Rupesh V.; Pant, Amit M.; Menghani, Sunil S.; Wadibhasme, Pankaj G.; Khedekar, Pramod B. South African Journal of Chemistry, 2013 , vol. 66, p. 254 - 262]

Copper-catalyzed synthesis of benzoxazoles via a regioselective C− H functionalization/C− O bond formation under an air atmosphere

[Ueda, Satoshi; Nagasawa, Hideko Journal of Organic Chemistry, 2009 , vol. 74, # 11 p. 4272 - 4277]

Direct arylation of benzoxazole C–H bonds with iodobenzene diacetates

[Yu, Peng; Zhang, Guangyou; Chen, Fan; Cheng, Jiang Tetrahedron Letters, 2012 , vol. 53, # 34 p. 4588 - 4590]

Parallel synthesis of a library of benzoxazoles and benzothiazoles using ligand-accelerated copper-catalyzed cyclizations of ortho-halobenzanilides

[Evindar, Ghotas; Batey, Robert A. Journal of Organic Chemistry, 2006 , vol. 71, # 5 p. 1802 - 1808]

More Articles...