2, 2′-Bipyridine: An Efficient Ligand in the Cobalt-Catalyzed Synthesis of Organozinc Reagents from Aryl Chlorides and Sulfonates

I Kazmierski, C Gosmini, JM Paris, J Périchon

Index: Kazmierski, Igor; Gosmini, Corinne; Paris, Jean-Marc; Perichon, Jacques Synlett, 2006 , # 6 p. 881 - 884

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Citation Number: 20

Abstract

Abstract The synthesis of functionalized arylzinc reagents from aromatic chlorides, triflates, or mesylates, via cobalt catalysis, is reported using 2, 2′-bipyridine as a ligand in a mixture of acetonitrile and pyridine. This procedure allows the synthesis of a variety of functionalized arylzinc species in good to excellent yields. Some of these arylzinc compounds have been coupled with aromatic bromides under palladium catalysis.