Ultrasound assisted one pot synthesis of imidazole derivatives using diethyl bromophosphate as an oxidant

…, P Mandhane, S Shingote, P Badadhe, C Gill

Index: Nagargoje, Deepak; Mandhane, Priyanka; Shingote, Savita; Badadhe, Pravin; Gill, Charansingh Ultrasonics Sonochemistry, 2012 , vol. 19, # 1 p. 94 - 96

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Citation Number: 35

Abstract

A one pot, three-component condensation of benzoin/benzyl, an aldehyde, and ammonium acetate using diethyl bromophosphate as a mild oxidant is achieved to form trisubstituted imidazole compounds. Under ultrasound irradiation, a smooth condensation occurs to get the 2, 4, 5-triaryl-1H-imidazole compounds in good to excellent yields. The study explores the scope and limitation of diethyl bromophosphate as an oxidant and suggests ...