Biocatalytic approach to enantiomerically pure β-amino acids
…, IP Shishkina, SV Galushko, AE Sorochinsky…
Index: Soloshonok; Fokina; Rybakova; Shishkina; Galushko; Sorochinsky; Kukhar; Savchenko; Svedas Tetrahedron Asymmetry, 1995 , vol. 6, # 7 p. 1601 - 1610
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Citation Number: 94
Abstract
β-Aryl-β-amino acids were prepared in good chemical yield and high enantiomeric purity (> 95% ee) via penicillin acylase-catalyzed hydrolysis of the corresponding N-phenylacetyl derivatives. The (R)-enantiomers were the fast-reacting isomers in all cases studied. The ...
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