Tetrahedron Letters

One-pot synthesis of unsymmetrical benzils from aryl methyl ketones and arenes in the presence of selenous acid catalysed by p-toluenesulfonic acid monohydrate

I Kharkongor, MR Rohman, B Myrboh

Index: Kharkongor, Icydora; Rohman, Md. Rumum; Myrboh, Bekington Tetrahedron Letters, 2012 , vol. 53, # 23 p. 2837 - 2841

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Citation Number: 5

Abstract

A modified one-pot method for the synthesis of unsymmetrical and heteroaryl benzils from substituted acetophenones and unactivated or weakly activated arenes by the use of H2SeO3 and p-TsOH· H2O as catalysts at 35° C is established. The present method is regioselective and avoids the use of p-TsOH· H2O in stoichiometric amount in the presence of H2SeO3 and afforded unsymmetrical benzils in good yields.

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