Microwave??Assisted One??Step Synthesis of Acetophenones via Palladium??Catalyzed Regioselective Arylation of Vinyloxytrimethylsilane

W Qian, L Zhang, H Sun, H Jiang…

Index: Qian, Wangke; Zhang, Lei; Sun, Haifeng; Jiang, Hualiang; Liu, Hong Advanced Synthesis and Catalysis, 2012 , vol. 354, # 17 p. 3231 - 3236

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Citation Number: 6

Abstract

Abstract The regiochemistry of the palladium-mediated arylation (Heck arylation) of enol ethers is sensitive to the structure of the enol ether, the arylating agent and the catalytic system. In this study, an effective and practical method was successfully developed for the synthesis of acetophenones with high regioselectivity under palladium-catalyzed conditions. A variety of acetophenones was readily prepared from aryl iodides in good to excellent ...

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