Photochemical generation of nitric oxide from 6-nitrobenzo [a] pyrene

K Fukuhara, M Kurihara, N Miyata

Index: Fukuhara; Kurihara; Miyata Journal of the American Chemical Society, 2001 , vol. 123, # 36 p. 8662 - 8666

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Citation Number: 82

Abstract

Photolabile 6-nitrobenzo [a] pyrene (6-nitroBaP) released nitric oxide (NO) under visible- light irradiation. The generation of NO and the concomitant formation of the 6-oxyBaP radical were confirmed by ESR. BaP quinones were also detected as further oxidized products of the 6-oxyBaP radical. No such photodegradation was observed with other nitrated BaPs, such as 1-nitroBaP and 3-nitroBaP. DNA-strand breakage, caused by photoexcited 6- ...