New fluorinating reagents. Part II. Preparation and Synthetic Application of a Saccharin Derived N??Fluorosultam
E Differding, RW Lang
Index: Differding, Edmond; Lang, Robert W. Helvetica Chimica Acta, 1989 , vol. 72, p. 1248 - 1252
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Citation Number: 78
Abstract
The synthesis of the new saccharin derived N-fluorosultam 1 is described. A comparative study with commer- cially available N-fluorosulfonamides shows 1 to be a superior fluorinating reagent for the synthesis of CI -fluoro- carbonyl compounds. ... 1. Introduction. - Fluorine substituents at biologically relevant positions of synthet:c drugs and pesticides are extremely effective modifiers of their reactivity, a fact, which has initiated an ever growing interest in selectively ...
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