Facile, One??Step Production of Niacin (Vitamin B3) and Other Nitrogen??Containing Pharmaceutical Chemicals with a Single??Site Heterogeneous Catalyst

…, JM Thomas, M Greenhill??Hooper…

Index: Raja, Robert; Thomas, John Meurig; Greenhill-Hooper, Michael; Ley, Steven V.; Almeida Paz, Filipe A. Chemistry - A European Journal, 2008 , vol. 14, # 8 p. 2340 - 2348

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Citation Number: 27

Abstract

Abstract Niacin (3-picolinic acid), which is extensively used as vitamin B 3 in foodstuffs and as a cholesterol-lowering agent, along with other oxygenated products of the picolines, 4- methylquinoline, and a variety of pyrimidines and pyridazines, may be produced in a single- step, environmentally benign fashion by combining single-site, open-structure, heterogeneous catalysts with a solid source of active oxygen, namely acetyl peroxyborate ...