Tetrahedron

In situ generation of palladium nanoparticles: ligand-free palladium catalyzed ultrafast Suzuki–Miyaura cross-coupling reaction in aqueous phase at room temperature

Z Du, W Zhou, F Wang, JX Wang

Index: Du, Zhengyin; Zhou, Wanwei; Wang, Fen; Wang, Jin-Xian Tetrahedron, 2011 , vol. 67, # 26 p. 4914 - 4918

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Citation Number: 38

Abstract

Abstract An ultrafast and highly efficient ligand-free Suzuki–Miyaura cross-coupling reaction between aryl bromides/iodides and arylboronic acids using palladium chloride as catalyst in PEG400/H 2 O in air at room temperature has been developed. TEM showed that palladium nanoparticles were generated in situ from PdCl 2/PEG400/H 2 O without use of other reductants. The catalyst system can be recycled to reuse three times with good yields.

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