Azole compounds designed by molecular modelling show antifungal activity as predicted

…, VM Gokhale, PS Kharkar, VM Kulkarni

Index: Karki, Rajeshri G.; Gokhale, Vijay M.; Kharkar, Prashant S.; Kulkarni, Vithal M. Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2003 , vol. 42, # 2 p. 372 - 381

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Abstract

Abstract: Rational approaches involving drug discovery technologies such as computational and combinatorial chemistry and high throughput screening have been useful tools to design and discover new drugs more efficiently. The interplay among structure-activity relationships, computer modelling, chemical synthesis and pharmacological testing can lead to better products for a particular therapeutic purpose. The work presented in this paper ...