Silica chloride (SiO2-Cl) and trimethylsilyl chloride (TMSCl) promote facile and efficient dehydration of tertiary alcohols
H Firouzabadi, N Iranpoor, H Hazarkhani…
Index: Firouzabadi, Habib; Iranpoor, Naser; Hazarkhani, Hassan; Karimi, Babak Synthetic Communications, 2003 , vol. 33, # 21 p. 3653 - 3660
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Citation Number: 14
Abstract
Abstract Silica chloride (SiO2-Cl), as a heterogeneous reagent, has been used for the efficient dehydration of tertiary alcohols under mild reaction conditions. For comparison, we have also used trimethylsilyl chloride (TMSCl) as a homogeneous reagent for this purpose. We have found that silica chloride is a more efficient reagnet than trimethylsilyl chloride for this purpose. Handling of SiO2-Cl is much safer and easier than TMSCl, especially for ...
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