Handling the limit of detection by extrapolation.
Nicholas T Longford
Index: Stat. Med. 31(26) , 3133-46, (2012)
Full Text: HTML
Abstract
A general method of estimation with a variable observed subject to a limit of detection is introduced. It is based on extrapolation of the estimates obtained by increasing the limit of detection. Theoretical arguments support the method in some special cases, and it is explored by simulations. Several examples are presented and adaptations for other kinds of censoring explored.Copyright © 2012 John Wiley & Sons, Ltd.
Related Compounds
Related Articles:
2014-10-01
[Diabetes 63(10) , 3483-96, (2014)]
Antioxidant and mitochondrial protective effects of oxidized metabolites of oltipraz.
2010-02-01
[Expert Opin. Drug Metab. Toxicol. 6(2) , 213-24, (2010)]
Inhibition of colon carcinogenesis by post-initiation induction of NQO1 in Sprague-Dawley rats.
2009-06-01
[Oncol. Rep. 21(6) , 1559-65, (2009)]
2009-04-01
[Arch. Pharm. Res. 32(4) , 625-35, (2009)]
Pharmacokinetic interaction between oltipraz and silymarin in rats.
2009-01-01
[J. Pharm. Pharm. Sci. 12(1) , 1-16, (2009)]