Copper-catalyzed cyanation of aryl iodide with the combined cyanide source of urea and DMSO
K Zheng, B Liu, S Chen, F Chen
Index: Zheng, Kui; Liu, Bin; Chen, Shuyou; Chen, Fan Tetrahedron Letters, 2013 , vol. 54, # 38 p. 5250 - 5252
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Citation Number: 4
Abstract
Abstract A simple copper-catalyzed cyanation of aryl iodide with the combination of urea and dimethyl sulfoxide as a cyanide source is achieved, providing nitriles in moderate to good yields. This new approach represents an exceedingly practical and safe method for the synthesis of aryl nitriles.
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