Bacterial L-arabinose isomerases: industrial application for D-tagatose production.

Samira Boudebbouze, Emmanuelle Maguin, Moez Rhimi

Index: Recent Pat. DNA Gene Seq. 5(3) , 194-201, (2011)

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Abstract

D-tagatose is a natural monosaccharide with a low caloric value and has an anti-hyperglycemiant effect. This hexose has potential applications both in pharmaceutical and agro-food industries. However, the use of D-tagatose remains limited by its production cost. Many production procedures including chemical and biological processes were developed and patented. The most profitable production way is based on the use of L-arabinose isomerase which allows the manufacture of D-tagatose with an attractive rate. Future developments are focused on the generation of L-arabinose isomerases having biochemical properties satisfying the industrial applications. This report provides a brief review of the most recent patents that have been published relating to this area.