Concise Syntheses of the Novel 1 H-Pyrrolo [3, 2-g] quinazoline Ring System and its [2, 3-f] Angular Isomer

…, L Sun, AD Sercel, RT Winters, WA Denny…

Index: Showalter, H. D. Hollis; Sun, Li; Sercel, Anthony D.; Winters, R. Thomas; Denny, William A.; Palmer, Brian D. Journal of Organic Chemistry, 1996 , vol. 61, # 3 p. 1155 - 1158

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Citation Number: 30

Abstract

Several years ago, Leonard and co-workers reported on the synthesis of a series of linear benzo-substituted purines, agents that act as purine mimics in many enzymatic reactions. 1 These are chemically designated as imidazo [4, 5-g] quinazolines and are exemplified by lin- benzohypoxanthine (1). There soon followed the synthesis of a number of angular analogues2 including the imidazo [4, 5-f] series of compounds exemplified by prox- ...