Biochemical and Biophysical Research Communications 2012-06-15

Catalposide is a natural agonistic ligand of peroxisome proliferator-activated receptor-α

Ji Hae Lee, Hee-jin Jun, Minh-Hien Hoang, Yaoyao Jia, Xiang Hua Han, Dong-Ho Lee, Hak-Ju Lee, Bang Yeon Hwang, Sung-Joon Lee

Index: Biochem. Biophys. Res. Commun. 422(4) , 568-72, (2012)

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Abstract

Highlights ► Catalposide is a novel ligand for PPARα. ► Cell stimulated with catalposide improved fatty acid uptake, regulated target genes in fatty acid β-oxidation and synthesis. ► Catalposdie reduces hepatic triacylglycerides. ► Theses demonstrate catalposide could ameliorate hyperlipidemia and hepatic steatosis.

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