[Gas chromatographic study of the composition of the volatile components of the urine in normal subjects and patients with diabetes mellitus].

N Inglik, B A Rudenko, I M Kakhnovskiĭ, T V Koroleva

Index: Lab. Delo (8) , 24-7, (1989)

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Abstract

The developed gas-chromatographic vapour-phase analysis of volatile components of biological fluids has been used to study the urine volatile organic compounds (VOC) in normal subjects and patients with diabetes mellitus. The results have permitted the detection of a normal urine VOC profile and helped define the range of individual shifts in the levels of some components. The findings evidence an increased excretion of methylketones and of lowest aliphatic alcohols in diabetes mellitus. The results of VOC analysis appear to be useful for the investigation of the nature of biochemical disorders of metabolism, for the diagnosis of diabetes mellitus decompensated forms, and for monitoring the efficacy of treatment for diabetes mellitus.