Tetrahedron letters

Copper-catalyzed coupling of aryl halides and nitrite salts: a mild Ullmann-type synthesis of aromatic nitro compounds

S Saito, Y Koizumi

Index: Saito, Shinichi; Koizumi, Yuichiro Tetrahedron Letters, 2005 , vol. 46, # 28 p. 4715 - 4717

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Citation Number: 55

Abstract

Nitration of aromatic halides proceeded smoothly in the presence of catalytic amounts of Cu bronze and N, N′-dimethylethylenediamine. Sodium nitrite-18-crown-6, or tetra-n- butylammonium nitrite (n-Bu4NNO2) turned out to be efficient nitrating agents. The aromatic nitro compounds were synthesized under essentially neutral conditions.

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