Synlett

An efficient synthesis of phenol via CuI/8-hydroxyquinoline-catalyzed hydroxylation of aryl halides and potassium hydroxide

S Maurer, W Liu, X Zhang, Y Jiang, D Ma

Index: Maurer, Stefan; Liu, Wei; Zhang, Xiaojing; Jiang, Yongwen; Ma, Dawei Synlett, 2010 , # 6 p. 976 - 978

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Citation Number: 28

Abstract

Abstract The CuI/8-hydroxyquinoline-catalyzed direct hydroxylation of aryl iodides with KOH takes place at 100 C in a mixed solvent system (t-BuOH-DMSO-H 2 O), providing the corresponding phenols in great diversity. Aryl bromides are found to be rather less reactive under these reaction conditions.

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