Tetrahedron Letters

Direct conversion of thiols and disulfides into sulfonamides

K Bahrami, MM Khodaei, M Soheilizad

Index: Bahrami, Kiumars; Khodaei, Mohammad M.; Soheilizad, Mehdi Tetrahedron Letters, 2010 , vol. 51, # 37 p. 4843 - 4846

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Citation Number: 26

Abstract

The H2O2–ZrCl4 reagent system is used as a new and efficient reagent for the conversion of thiols and disulfides into sulfonamides. The protocol offers several advantages such as excellent yields of products and extremely fast reactions at room temperature. The reagent system is very easy to handle and is environmentally safe and economical.

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