Tetrahedron Letters

DMC mediated one pot synthesis of biaryl ketones from aryl carboxylic and boronic acids

A Pathak, CS Rajput, PS Bora, S Sharma

Index: Pathak, Arunendra; Rajput, Chatrasal S.; Bora, Pushkar S.; Sharma, Somesh Tetrahedron Letters, 2013 , vol. 54, # 17 p. 2149 - 2150

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Citation Number: 6

Abstract

Ketone functionality in organic chemistry has been recognized as a moiety of immense utility. 1 Chemically, it represents a group which gives an immense opportunity to conduct nucleophilic and reductive addition reactions. In drug discovery projects, this acts as an important H-bond acceptor and acts as a modifier in the control of metabolism. ... Though the cross coupling method for the synthesis of ketones has advanced from previous methods, these methods require ...

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