Solid-state and solvent-free synthesis of azines, pyrazoles, and pyridazinones using solid hydrazine
B Lee, P Kang, KH Lee, J Cho, W Nam, WK Lee…
Index: Lee, Byeongno; Kang, Philjun; Lee, Kyu Hyung; Cho, Jaeheung; Nam, Wonwoo; Lee, Won Koo; Hur, Nam Hwi Tetrahedron Letters, 2013 , vol. 54, # 11 p. 1384 - 1388
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Citation Number: 23
Abstract
Azines, pyrazoles, and pyridazinones were isolated as the sole products in high yields (> 97%) by grinding solid hydrazine (H3N+ NHCO2−) with di-carbonyl compounds or by their reaction in the absence of solvent. Neither catalysts nor additives were needed to promote the reactions. The solid-state and solvent-free reactions proceeded under ambient conditions and did not produce any wastes other than water and carbon dioxide. They are ...
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