Isocyanatophosphoric acid dichloride: A novel reagent for the introduction of a cyano group into the molecules of electron-rich heterocycles and enamines

…, AA Chaikovskaya, AM Pinchuk, AA Tolmachev

Index: Smaliy, Radomir V.; Chaikovskaya, Aleksandra A.; Pinchuk, Aleksandr M.; Tolmachev, Andrei A. Synthesis, 2002 , # 16 p. 2416 - 2420

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Citation Number: 12

Abstract

Herein we report isocyanatophosphoryl dichloride (the Kirsanov isocyanate) [5] as an easily accessible and convenient reagent for the introduction of a cyano group into electron-rich heterocycles and enamines. As was reported by us previously, the Kirsanov isocyanate dissolved in octane readily acylates electron-rich heterocycles to furnish, in good yields, N-dichlorophosphorylheterylcarboxamides. [6] Here we have found that the latter ...

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