The Journal of Organic Chemistry

Advances in the chemistry of 2, 3-epoxyalcohols. New methodology for contra-trans-diaxial opening and selective enediol oxidation

BA McKittrick, B Ganem

Index: McKittrick, Brian A.; Ganem, Bruce Journal of Organic Chemistry, 1985 , vol. 50, # 26 p. 5897 - 5898

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Citation Number: 47

Abstract

Advances in the Chemistry of 2,3-Epoxy Alcohols. New Methodology for Contra-Trans-Diaxial Opening and Selective Enediol Oxidation ... Summary: A selenoaluminum-mediated, contra-trans- diaxial epoxide opening and a selective enediol-to-hydroxy enone oxidation have been developed for the total syn- thesis of bioactive quassinoids. ... Sir: Interest in the antileukemic and antineoplastic properties of pentacyclic quassinoids has prompted several research ...

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