Journal of Pharmaceutical Sciences 1980-12-01

N-Demethylation of dextromethorphan.

N P Peet

Index: J. Pharm. Sci. 69(12) , 1447-8, (1980)

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Abstract

In addition to providing an efficient synthesis of 3-methoxymorphinan hydrochloride, the use of 2,2,2-trichloroethyl chloroformate in the N-demethylation of dextromethorphan led to the isolation of two novel zinc salts of 3-methoxymorphinan.


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