A concise total synthesis of amphidinolide T2.
Huoming Li, Jinlong Wu, Jialu Luo, Wei-Min Dai
Index: Chemistry 16(38) , 11530-4, (2010)
Full Text: HTML
Abstract
RCM + AD = T2: In the presence of the C16-methylene group, regioselective ring-closing metathesis (RCM) formed the (12E)-endocyclic double bond, which underwent Os-catalyzed asymmetric dihydroxylation (AD) to give the desired 12,13-diol intermediate required for the total synthesis of amphidinolide T2 in 16 linear steps in 8.0% overall yield.Copyright © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Related Compounds
Related Articles:
2012-06-20
[J. Am. Chem. Soc. 134(24) , 10089-101, (2012)]
Group 4 salalen complexes for the production and degradation of polylactide.
2011-09-28
[Chem. Commun. (Camb.) 47(36) , 10004-6, (2011)]
Self-organization of lactates in the gas phase.
2003-12-07
[Org. Biomol. Chem. 1(23) , 4351-8, (2003)]
A pitfall associated with lactate detection using stimulated-echo proton spectroscopy.
1991-02-01
[Magn. Reson. Med. 17(2) , 533-8, (1991)]
Single-scan volume-selective spectral editing by homonuclear polarization transfer.
1989-02-01
[Magn. Reson. Med. 9(2) , 254-60, (1989)]