Cyclizations by carbon monoxide in Friedel-Crafts reactions. Facile synthesis of. beta.-disubstituted. alpha.-indanones

HA Bruson, HL Plant

Index: Bruson,H.A.; Plant,H.L. Journal of Organic Chemistry, 1967 , vol. 32, p. 3356 - 3362

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Citation Number: 18

Abstract

The isomerization of the dihalobutanes other than the 1, 4 isomer in the presence of AlCl3 to give 2, 2-dimethylindanone under the Friedel-Crafts conditions used is reconcilable with an observation made by Sommer'that 1, 3-dibromobutane is isomerized at 25" by A1Br3 to form a mixture of 1, 2-, 2, 3-, 2, 2-, 1, l-, and 1, 3-dibromobutanes with only traces of 1, 4- dibromobutane. Presumably 1, 4-dichlorobutane behaves similarly. It was therefore of ...