A comparison of three methods of hydrolysis for estrogen conjugates.
J D Bain, L H Kasman, A B Bercovitz, B L Lasley
Index: Steroids 43(6) , 603-19, (1984)
Full Text: HTML
Abstract
The efficiencies for estrogen conjugate hydrolysis were compared between enzyme hydrolysis, acid solvolysis and a new method, ammonolysis. Samples included: 1) crystalline 1,3,5(10)-estratriene-3, 17 beta-diol disulfate (estradiol 3,17-disulfate), 2) squirrel monkey urine collected following an intravenous injection of [2,4,6,7-H] 1,3,5(10)-estratriene-3,17 beta-diol (estradiol) and 3) a pool of human pregnancy urine. Ammonolysis demonstrated a significant increase over the other techniques in "free" estrogen yields, specifically, from estradiol 3,17-disulfate.
Related Compounds
Related Articles:
Selective inhibition of glutathione S-transferases by 17 beta-estradiol disulfate.
1977-04-15
[Arch. Biochem. Biophys. 180 , 186-190, (1977)]
Novel regulators of Fgf23 expression and mineralization in Hyp bone.
2009-09-01
[Mol. Cancer Ther. 23 , 1505-18, (2009)]
Why amphibians are more sensitive than mammals to xenobiotics.
2009-01-01
[PLoS ONE 4 , e7699, (2009)]
[Hormonal supplement therapy in women: effects on the cardiovascular system].
2001-01-13
[Ned. Tijdschr. Geneeskd. 145(2) , 65-9, (2001)]
2001-07-23
[Bioorg. Med. Chem. Lett. 11(14) , 1839-42, (2001)]