[Study on the bioactive constituents of Piper wallichii].
Guo-Wei Zhao, Wen Xia, Ping Chen, En-Ji Han, Lan Xiang
Index: Zhong Yao Cai 35(1) , 53-6, (2012)
Full Text: HTML
Abstract
To investigate the bioactive constituents in the stem of Piper wallichii.Compounds were separated by column chromatography of silica gel, ODS-A and Sephadex LH-20. Their structures were elucidated based on spectral analysis. DPPH scavenging activity and AchE inhibitory activity were tested.10 compounds were isolated and their structures were identified as 3,4-methylenedioxy-benzoic acid (1), vanillic acid (2), benzoic acid (3), N-p-coumaroyltyramine (4), futoenone (5), futoquinol (6), isofutoquinol A (7), 4-hydroxy-3,5-dimethoxy-benzoic acid (8), futoamide (9), dihydropiperlonguminine (10).Compounds 1-6 are isolated from P. wallichii for the first time. Vanillic acid (2) and 4-hydroxy-3,5-dimethoxy-benzoic acid (8) show scavenging activity against DPPH radical with ED50 at 224.33 microg/mL and 11.44 microg/mL, respectively. No compound shows inhibition activity against AchE.
Related Compounds
Related Articles:
Antimicrobial activity of natural products from the flora of Northern Ontario, Canada.
2015-06-01
[Pharm. Biol. 53(6) , 800-6, (2015)]
2016-03-01
[Food Chem. 194 , 671-9, (2015)]
Antagonistic control of a dual-input mammalian gene switch by food additives.
2014-08-01
[Nucleic Acids Res. 42(14) , e116, (2014)]
Synthesis and accumulation of aromatic aldehydes in an engineered strain of Escherichia coli.
2014-08-20
[J. Am. Chem. Soc. 136(33) , 11644-54, (2014)]
Optimization of antioxidant phenolic compounds extraction from quinoa (Chenopodium quinoa) seeds.
2015-07-01
[J. Food Sci. Technol. 52 , 4396-404, (2015)]