ACS combinatorial science

Solid-Phase Synthesis of 2-Aryl-3-alkylamino-1 H-indoles from 2-Nitro-N-(2-oxo-2-arylethyl) benzenesulfonamides via Base-Mediated C-Arylation

E Schütznerová, V Krchňák

Index: Ramirez-Martinez, Juan F.; Gonzalez-Chavez, Rodolfo; Guerrero-Alba, Raquel; Reyes-Gutierrez, Paul E.; Martinez, Roberto; Miranda-Morales, Marcela; Espinosa-Luna, Rosa; Gonzalez-Chavez, Marco M.; Barajas-Lopez, Carlos Molecules, 2013 , vol. 18, # 1 p. 894 - 913

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Citation Number: 4

Abstract

... of heterocycles such as the 4,7,8-trisubstituted 1,2,3,4-tetrahydrobenzo[e][1,4 ... Indole-containing molecules exhibit a remarkably wide range of biological activities, and these compounds have been referred ... a Reagents and conditions: (i) 0.1–0.5 M base, DMF or DMSO, rt to 50 °C ...

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