Hydrogen-bonding-promoted oxidative addition and regioselective arylation of olefins with aryl chlorides
J Ruan, JA Iggo, NG Berry, J Xiao
Index: Ruan, Jiwu; Iggo, Jonathan A.; Berry, Neil G.; Xiao, Jianliang Journal of the American Chemical Society, 2010 , vol. 132, # 46 p. 16689 - 16699
Full Text: HTML
Citation Number: 55
Abstract
The first, general, and highly efficient catalytic system that allows a wide range of activated and unactivated aryl chlorides to couple regioselectively with olefins has been developed. The Heck arylation reaction is likely to be controlled by the oxidative addition of ArCl to Pd (0). Hence, an electron-rich diphosphine, 4-MeO-dppp, was introduced to facilitate the catalysis. Solvent choice is critical, however; only sluggish arylation is observed in DMF or ...
Related Articles:
[McNulty, James; Das, Priyabrata European Journal of Organic Chemistry, 2009 , # 24 p. 4031 - 4035]
Synthesis of cicerfuran, an antifungal benzofuran, and some related analogues
[Aslam, Shazia N.; Stevenson, Philip C.; Phythian, Sara J.; Veitch, Nigel C.; Hall, David R. Tetrahedron, 2006 , vol. 62, # 17 p. 4214 - 4226]
[Alonso, Francisco; Riente, Paola; Yus, Miguel European Journal of Organic Chemistry, 2009 , # 34 p. 6034 - 6042]
[Aguirre, J. M .; Alesso, E. N.; Ibanez, A. F.; Tombari, D. G.; Moltrasio Iglesias G. Y. Journal of Heterocyclic Chemistry, 1989 , vol. 26, p. 25 - 27]
Amine??and Sulfonamide??Promoted Wittig Olefination Reactions in Water
[McNulty, James; McLeod, David Chemistry - A European Journal, 2011 , vol. 17, # 32 p. 8794 - 8798]