Synthesis and properties of 5-chloro-4-nitropyrazoles

…, LI Larina, AN Mirskova, GG Levkovskaya

Index: Bozhenkov; Savosik; Larina; Mirskova; Levkovskaya Russian Journal of Organic Chemistry, 2006 , vol. 42, # 6 p. 901 - 906

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Citation Number: 9

Abstract

Abstract The nitration of 5-chloropyrazoles with a mixture of 100% nitric acid and 65% oleum or a mixture of 60% nitric acid and polyphosphoric acid gave substituted 5-chloro-4- nitropyrazoles in 45–91% yield. The nitration of 3-aryl-5-halopyrazoles was accompanied by introduction of a nitro group into the aromatic ring. 4-Chloropyrazoles failed to undergo nitration under these conditions. The reaction of 5-chloro-1, 3-dimethyl-4-nitropyrazole ...