Synthesis of [2H, 13C]??Labelled Diallylmalonates− Useful Probes for the Study of Transition Metal??Catalysed 1, 6??Diene Cycloisomerisation

KL Bray, GC Lloyd??Jones

Index: Bray, Katharine L.; Lloyd-Jones, Guy C. European Journal of Organic Chemistry, 2001 , # 9 p. 1635 - 1642

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Citation Number: 9

Abstract

Abstract Reliable synthetic routes to isotopically labelled dimethyl [13 C, 2 H] diallylmalonates (1) have been developed. Dimethyl diallylmalonates readily undergo transition-metal catalysed cycloisomerisation and the isotopically labelled substrates are expected to be of general utility in the study of the mechanism of such reactions. In the synthetic routes developed, the 2 H labelled allyl chains were introduced by reduction of ...

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