Antimalarials: Synthesis of 4??aminoquinolines that circumvent drug resistance in malaria parasites
D De, LD Byers, DJ Krogstad
Index: Journal of Heterocyclic Chemistry, , vol. 34, # 1 p. 315 - 320
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Citation Number: 65
Abstract
... J. Heterocyclic Chem, 34, 315 (1997). ... quine, and multiply-resistant P. falciparum is being reported in detail elsewhere [6]. HN J\/\/NEI2 / lid Cl N Figure 1. Chloroquine Chemistry. ... 2.52 (q, 4H, J = 7.5, NCH2), 3.29 (q, 2H, J: 5.5, NCH2), 4.98 (bs, 1H, NH), 6.42 (d, 1H, J = 5.5, AIC3 ...
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