Design, synthesis and preliminary bioactivity studies of 1, 3, 4-thiadiazole hydroxamic acid derivatives as novel histone deacetylase inhibitors

P Guan, F Sun, X Hou, F Wang, F Yi, W Xu…

Index: Bioorganic and Medicinal Chemistry, , vol. 20, # 12 p. 3865 - 3872

Full Text: HTML

Citation Number: 30

Abstract

... Bioorganic & Medicinal Chemistry. ... a Department of Medicinal Chemistry, Key Laboratory ... b Department of Pharmacology, Shandong University, School of Medicine, Ji'nan, Shandong 250012, PR China. Received 25 February 2012, Revised 13 April 2012, Accepted 16 April 2012 ...

Related Articles:

Enantioselective synthesis of PsiA. beta., a sporogenic metabolite of Aspergillus nidulans

[Mazur, Paul; Nakanishi, Koji Journal of Organic Chemistry, 1992 , vol. 57, # 3 p. 1047 - 1051]

A possible improvement for structure-based drug design illustrated by the discovery of a Tat HIV-1 inhibitor

[Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 6 p. 1543 - 1546]

Obtention de la lactone de prelog-djerassi et d'autres δ-lactones par addition du pentenyltrimethylsilane sur des derives de l'anhydride glutarique

[Tetrahedron Letters, , vol. 25, # 39 p. 4371 - 4374]

More Articles...