[Palladium-containing compounds possess radiation-protective properties and enhance adaptive response of CFUs to radiation].

T N Semenets, O V Semina, I A Efimenko, N A Ivanova, A M Poverennyĭ

Index: Radiats. Biol. Radioecol. 37(6) , 892-5, (1997)

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Abstract

Efasol and potassium tetrachloropalladate being injected into mice prior to irradiation with a dose of 150 sGy increase the colony forming activity of animals bone marrow cells transplanted in lethally irradiated recipient mice. The palladium presence in such compounds is supposed to be a reason of radioprotection. Upon the combined application of potassium tetrachloropalladate and irradiation of mice with an adaptive dose of 5 sGy a potentiation of individual effect of each separate agent to increase CFUs resistance against the consequent irradiation was observed.