Synthesis of Nanogels via Cell Membrane-Templated Polymerization.

Jianhua Zhang, Weiwei Gao, Ronnie H Fang, Anjie Dong, Liangfang Zhang

Index: Small 11 , 4309-13, (2015)

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Abstract

The synthesis of biomimetic hydrogel nanoparticles coated with a natural cell membrane is described. Compared to the existing strategy of wrapping cell membranes onto pre-formed nanoparticle substrates, this new approach forms the cell membrane-derived vesicles first, followed by growing nanoparticle cores in situ. It adds significant controllability over the nanoparticle properties and opens unique opportunities for a broad range of biomedical applications. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.