Palladium (0)??Mediated Rapid Methylation and Fluoromethylation on Carbon Frameworks by Reacting Methyl and Fluoromethyl Iodide with Aryl and Alkenyl Boronic …
I Ban, A Nonoyama, K Sumi, C Kuang…
Index: Doi, Hisashi; Ban, Ikuya; Nonoyama, Akihito; Sumi, Kengo; Kuang, Chunxiang; Hosoya, Takamitsu; Tsukada, Hideo; Suzuki, Masaaki Chemistry - A European Journal, 2009 , vol. 15, # 16 p. 4165 - 4171
Full Text: HTML
Citation Number: 45
Abstract
Abstract A new synthetic methodology for the rapid methylation and fluoromethylation on aryl and alkenyl frameworks by using methyl and fluoromethyl iodide with an organoboronic acid ester has been developed under the simple and mild conditions of [Pd 2 (dba) 3]/P (o- CH 3 C 6 H 4) 3/K 2 CO 3 (dba= dibenzylideneacetone) in DMF at 60 C for 5 min (see scheme). This boron protocol provides a firm chemical basis for the synthesis of 11 C-and ...
Related Articles:
[Organometallics, , vol. 30, # 17 p. 4687 - 4694]
NHC Complexes of Cobalt (II) Relevant to Catalytic C–C Coupling Reactions
[Organometallics, , vol. 32, # 3 p. 723 - 732]
[Kikukawa, Kiyoshi; Kono, Kiyoshi; Wada, Fumio; Matsuda, Tsutomu Journal of Organic Chemistry, 1983 , vol. 48, # 8 p. 1333 - 1336]
[Helvetica Chimica Acta, , vol. 72, p. 570 - 593]
Methylation of aromatics with Me 3 S+, Me 3 Se+, and Me 3 Te+ in superacid media
[Journal of Organometallic Chemistry, , vol. 348, p. 199 - 204]