Studies on pyrrolidinones. On the application of copper-catalyzed arylation of methyl pyroglutamate to obtain a new benzo [de] quinoline scaffold
…, S Oudir, JP Hénichart, B Rigo, N Pommery, P Gautret
Index: Ghinet, Alina; Oudir, Souhila; Henichart, Jean-Pierre; Rigo, Benoit; Pommery, Nicole; Gautret, Philippe Tetrahedron, 2010 , vol. 66, # 1 p. 215 - 221
Full Text: HTML
Citation Number: 9
Abstract
Optimized conditions for copper-catalyzed N-arylation of methyl pyroglutamate are described. These studies permitted the synthesis of methyl N-naphthylpyroglutamate, which was then cyclized to a ketone. The known dehydration of amidoketones by PPA was extended to this new scaffold to lead to a novel condensed benzo [de] quinoline with potential antioxidative activity.
Related Articles:
[Trusova, Marina E.; Krasnokutskaya, Elena A.; Postnikov, Pavel S.; Choi, Younghwa; Chi, Ki-Whan; Filimonov, Victor D. Synthesis, 2011 , # 13 p. 2154 - 2158]
Microwave-assisted methylation of phenols with DMF-DMA
[Belov, Pavel; Campanella, Veronica L.; Smith, Alison W.; Priefer, Ronny Tetrahedron Letters, 2011 , vol. 52, # 21 p. 2776 - 2779]
REGIOSELECTIVE OXYIODINATION OF AROMATIC COMPOUNDS USING POTASSIUM IODIDE AND OXONE®*
[Synthetic Communications, , vol. 32, # 15 p. 2319 - 2324]
Aryliodine (III) diacetates as substrates for Pd–Ag catalyzed arylation of alkenes
[Evdokimov, Nikolai M.; Kornienko, Alexander; Magedov, Igor V. Tetrahedron Letters, 2011 , vol. 52, # 33 p. 4327 - 4329]
[Satyamurthy, Nagichettiar; Barrio, Jorge R. Journal of Organic Chemistry, 1983 , vol. 48, # 23 p. 4394 - 4396]