Convenient processes for the synthesis of aromatic ketones from aryl bromides and carboxylic anhydrides using a cobalt catalysis

I Kazmierski, M Bastienne, C Gosmini…

Index: Kazmierski, Igor; Bastienne, Mylene; Gosmini, Corinne; Paris, Jean-Marc; Perichon, Jacques Journal of Organic Chemistry, 2004 , vol. 69, # 3 p. 936 - 942

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Citation Number: 54

Abstract

The cross-coupling of various para-and meta-substituted aromatic bromides, mostly bearing sensitive moieties, with several carboxylic acid anhydrides is reported. This reaction can be carried out in two steps, by forming an aromatic organozinc reagent via cobalt catalysis in the first step, or even more interestingly in a single step, also by using a cobalt-based catalyst. The aromatic ketones are obtained by these new, mild, and convenient methods ...

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